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September 1999, Week 4

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"Iowa Discussion, Alerts and Announcements" <[log in to unmask]>
Subject:
O: Antimicrobial growth promoters
From:
jrclark <[log in to unmask]>
Date:
Tue, 28 Sep 1999 13:44:10 -0500
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Reply-To:
"Iowa Discussion, Alerts and Announcements" <[log in to unmask]>
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Forwarded by Jane Clark at [log in to unmask]

Roy Overton is a retired doctor, and an activist and lobbyist for Izaak
Walton League.

----------
From: Roy Overton <[log in to unmask]>
Subject: Fw: antimicrobial growth promoters
Date: Tuesday, September 28, 1999 10:45 PM

F Y I....Fellow Ikes and members of the Environmental Health
committee....this challenge ahead of us about using antibiotics
prohylactically in feeds to animals is important to humans also, with
resistances and cross-resistances with drugs used for humans....also, these
resistant organisims have a way of getting to humans on catheters, heart
valves and artificial vessels etc. We must  always remember that
inappropriate use of  antibiotics by doctors....for inappropriate
diagnosis, improper length of time, improper doseages etc. is a common
problem also

We may wonder at times how this fits with the Ike's issues, but this is
very important in our environment...as important as inappropriate use of AG
chemicals and polluted water.

roy overton MD....chair of the environmental health committee of the
national ikes.
-----Original Message-----
From: kywaters <[log in to unmask]>
To: CWA feedlots <[log in to unmask]>
Date: Tuesday, September 28, 1999 1:45 AM
Subject: antimicrobial growth promoters

http://id.medscape.com/govmt/CDC/EID/1999/v05.n03/e0503.03.wege/e0503.03.weg
e-01.html

From
Emerging Infectious Diseases

Use of Antimicrobial Growth Promoters in Food Animals and Enterococcus
faecium Resistance to Therapeutic Antimicrobial Drugs in Europe

Henrik C. Wegener, Frank M. Aarestrup, Lars Bogų Jensen, Anette M.
Hammerum, and Flemming Bager, Danish Veterinary Laboratory, Copenhagen,
Denmark
------------------------------------------------------------------------
Abstract
Supplementing animal feed with antimicrobial agents to enhance growth has
been common practice for more than 30 years and is estimated to constitute
more than half the total antimicrobial use worldwide. The potential public
health consequences of this use have been debated; however, until recently,
clear evidence of a health risk was not available. Accumulating evidence
now indicates that the use of the glycopeptide avoparcin as a growth
promoter has created in food animals a major reservoir of Enterococcus
faecium, which contains the high level glycopeptide resistance determinant
vanA, located on the Tn1546 transposon. Furthermore, glycopeptide-resistant
strains, as well as resistance determinants, can be transmitted from
animals to humans. Two antimicrobial classes expected to provide the future
therapeutic options for treatment of infections with vancomycin-resistant
enterococci have analogues among the growth promoters, and a huge animal
reservoir of resistant E. faecium has already been created, posing a new
public health problem. [Emerging Infectious Diseases 5(3), 1999. Centers
for Disease Control]

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