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X-ASG-Orig-Subj: Public kept in dark on Roundup link to birth defects
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Subject: Public kept in dark on Roundup link to birth defects
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There is a report from Europe dealing with birth defects in animals linked
to glyphosate / Roundup - 52 pages long and I've not yet read through it -
but the gist is that European regulators were aware of a link to Monsanto's
flagship product more than 20 years ago and have kept this under wraps.  The
full report is available at:
http://www.scribd.com/doc/57277946/RoundupandBirthDefectsv5

This is actually of even greater concern to us in North America because we
grow more Roundup Ready crops and spray them with more Roundup, and our
regulators have increased the allowable amounts of Roundup that can be
applied.  Those who need to be most concerned are pregnant women or women
who may become pregnant who are living where Roundup may be sprayed, who may
be exposed to the drift, etc.   (I would also advise any woman who is
pregnant or may become pregnant not to use that product at home.)  When
drugs are reviewed for safety, those that cause malformations in animals are
labeled as a risk to pregnant women, and animal studies are regarded as a
pretty good indicator.  Human studies have not been done and would not be
ethical - but there have been reports of a high incidence of birth defects
in agricultural communities exposed to pesticide drift in South America
where Roundup Ready soy is grown, so there is ample cause for concern.  

      Jim Diamond, M.D.
      
---
*Public kept in the dark on Roundup link with birth defects
*Industry knew since 1980s, regulators since 1990s
Earth Open Source
Press release for immediate release, 7 June 2011
Contact: [log in to unmask]

Industry and EU regulators knew as long ago as the 1980s-1990s that Roundup,
the world's best selling herbicide, causes birth defects - but they failed
to inform the public. This is the conclusion of a new report, "Roundup and
birth defects: Is the public being kept in the dark?" co-authored by a group
of international scientists and researchers and released today.[1]

The report reveals that industry's own studies (including one commissioned
by Monsanto) showed as long ago as the 1980s that Roundup's active
ingredient glyphosate causes birth defects in laboratory animals.

The German government has known about these findings since at least the
1990s, when as the "rapporteur" member state for glyphosate, it reviewed
industry's studies for the EU approval of the herbicide. The European
Commission has known since at least 2002, when it signed off on glyphosate's
approval.

But this information was not made public. On the contrary, regulators have
consistently misled the public about glyphosate's safety. As recently as
last year, the German Federal Office for Consumer Protection and Food
Safety, BVL, told the Commission there was "no evidence of teratogenicity"
(ability to cause birth defects) for glyphosate.

BVL made this comment in its rebuttal[2] of an independent scientific study
published last year by Argentine scientists. The study showed that Roundup
and glyphosate cause birth defects in frogs and chickens at concentrations
much lower than those used in agricultural spraying.[3] The study was
prompted by reports of high rates of birth defects and cancers in areas of
South America growing genetically modified (GM) Roundup Ready soy, which is
engineered to tolerate being sprayed liberally with glyphosate herbicide.

In its rebuttal of the Argentine study, BVL cited as proof of glyphosate's
safety the industry studies submitted for the Commission's 2002 approval of
glyphosate (the approval that is currently in force).

But the authors of the new report obtained the approval documents and found
that contrary to BVL's claim, industry's own studies, conducted in the 1980s
and 1990s, showed that glyphosate/Roundup causes birth defects in
experimental animals. In some cases, these effects occurred at low doses.

The German authorities and the EU Commission's ECCO expert review panel[4]
whitewashed the findings and the Commission approved the herbicide.

Claire Robinson, a co-author of the new report and spokesperson for the
sustainability NGO Earth Open Source, which published it, said, "This looks
like a thirty-year cover-up by industry and regulators and it has certainly
placed the public at risk. Roundup is used not only by farmers but by home
gardeners and in school grounds and other public areas, in part because of
false marketing claims that it is safe."

Commission delays review of glyphosate

A new, more stringent pesticide regulation comes into force in the EU this
June. An objective review of glyphosate under this new regulation would
almost certainly result in a ban. This is because under the regulation,
independent studies have to be taken into consideration. Many of these
studies, summarised in the new report, show that glyphosate and Roundup
cause birth defects, cancer, genetic damage, endocrine disruption, and other
serious effects, often at very low doses.

Glyphosate was due to be reviewed in 2012. But late last year, the
Commission quietly passed a directive delaying the review of glyphosate and
38 other pesticides until 2015.[5]

Moreover, in 2015, glyphosate will be reviewed under lax, outdated
standards. This is because the Commission has failed to complete the data
requirements (the tests that industry has to do) for the new regulation in
time for industry to do the new tests. So glyphosate will likely sail
through its 2015 review and will not be reviewed under up-to-date, more
stringent data requirements for another 15 years, in 2030.[6]

Claire Robinson said, "Glyphosate could get a free regulatory ride until
2030, at a time when biotech companies are pressuring the EU for permission
to cultivate glyphosate-tolerant GM seeds in Europe. This would lead to a
huge increase in the use of glyphosate in Europe, as has happened in North
and South America. The beneficiary of the Commission's delay will be the
pesticide industry; the victim will be public health.

"The Commission must cancel the delay and conduct an immediate review of
glyphosate and Roundup, taking into consideration the independent scientific
literature. In the meantime, it must apply the precautionary principle and
withdraw the herbicide from use in Europe until the review has been
completed."

ENDS

References

1. Antoniou, M., Habib, M., Howard, C.V., Jennings, R.C., Leifert, C.,
Nodari, R. O., Robinson, C., Fagan, J. 2011. Roundup and birth defects: Is
the public being kept in the dark? Earth Open Source. June.
http://www.scribd.com/doc/57277946/RoundupandBirthDefectsv5

2. BVL, Germany. 2010. Glyphosate - Comments from Germany on the paper by
Paganelli, A. et al. (2010): "Glyphosate-based Herbicides Produce
Teratogenic Effects on Vertebrates by Impairing Retinoic Acid Signaling".
October 19.
http://www.powerbase.info/index.php/File:BVL2010.comments.Paganelli.pdf

3. Paganelli, A., Gnazzo, V. et al. 2010. Glyphosate-based herbicides
produce teratogenic effects on vertebrates by impairing retinoic acid
signaling. Chem Res Toxicol 23(10): 1586-1595.

4. This review role is now performed by the EFSA's PPR Panel.

5. European Commission. 2010. Commission Directive 2010/77/EU of 10 November
2010 amending Council Directive 91/414/EEC as regards the expiry dates for
inclusion in Annex I of certain active substances. OJ L 230, 19.8.1991.

6. The detailed reasons for this delay are explained in the new report.
Details as above.

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<P DIR=3DLTR><SPAN LANG=3D"en-us"><FONT FACE=3D"Calibri">There is a re=
port from Europe dealing with birth defects in animals li</FONT></SPAN=
><SPAN LANG=3D"en-us"><FONT FACE=3D"Calibri">nked to glyphosate / Roun=
dup</FONT></SPAN><SPAN LANG=3D"en-us"> <FONT FACE=3D"Calibri">&#8211;<=
/FONT></SPAN><SPAN LANG=3D"en-us"><FONT FACE=3D"Calibri"> 52</FONT> <F=
ONT FACE=3D"Calibri">pages long and I</FONT></SPAN><SPAN LANG=3D"en-us=
"><FONT FACE=3D"Calibri">&#8217;</FONT></SPAN><SPAN LANG=3D"en-us"><FO=
NT FACE=3D"Calibri">ve not yet read through it</FONT></SPAN><SPAN LANG=
=3D"en-us"> <FONT FACE=3D"Calibri">&#8211;</FONT></SPAN><SPAN LANG=3D"=
en-us"><FONT FACE=3D"Calibri"> but</FONT> <FONT FACE=3D"Calibri">the=
 gist is that European regulators were aware of a link to</FONT></SPAN=
><SPAN LANG=3D"en-us"><FONT FACE=3D"Calibri"> Monsanto</FONT></SPAN><S=
PAN LANG=3D"en-us"><FONT FACE=3D"Calibri">&#8217;</FONT></SPAN><SPAN=
 LANG=3D"en-us"><FONT FACE=3D"Calibri">s flagship product more</FONT>=
 <FONT FACE=3D"Calibri">than 20 years ago and have</FONT></SPAN><SPAN=
 LANG=3D"en-us"> <FONT FACE=3D"Calibri">kept this under wraps.&nbsp;=
 The full report is available at</FONT></SPAN><SPAN LANG=3D"en-us"><FO=
NT FACE=3D"Calibri">:</FONT><FONT FACE=3D"Calibri"></FONT></SPAN><SPAN=
 LANG=3D"en-us"> </SPAN><A HREF=3D"http://www.scribd.com/doc/57277946/=
RoundupandBirthDefectsv5"><SPAN LANG=3D"en-us"><U><FONT COLOR=3D"#0000=
FF" FACE=3D"Calibri">http://www.scribd.com/doc</FONT></U></SPAN><SPAN=
 LANG=3D"en-us"><U><FONT COLOR=3D"#0000FF" FACE=3D"Calibri">/</FONT></=
U></SPAN><SPAN LANG=3D"en-us"><U><FONT COLOR=3D"#0000FF" FACE=3D"Calib=
ri">57277946</FONT></U></SPAN><SPAN LANG=3D"en-us"><U><FONT COLOR=3D"#=
0000FF" FACE=3D"Calibri">/</FONT></U></SPAN><SPAN LANG=3D"en-us"><U><F=
ONT COLOR=3D"#0000FF" FACE=3D"Calibri">RoundupandBirthDefectsv5</FONT>=
</U></SPAN><SPAN LANG=3D"en-us"></SPAN></A><SPAN LANG=3D"en-us"></SPAN=
></P>

<P DIR=3DLTR><SPAN LANG=3D"en-us"><FONT FACE=3D"Calibri">This is actua=
lly of</FONT></SPAN><SPAN LANG=3D"en-us"> <FONT FACE=3D"Calibri">even<=
/FONT></SPAN><SPAN LANG=3D"en-us"> <FONT FACE=3D"Calibri">greater conc=
ern to u</FONT><FONT FACE=3D"Calibri">s in North America</FONT> <FONT=
 FACE=3D"Calibri">because</FONT></SPAN><SPAN LANG=3D"en-us"> <FONT FAC=
E=3D"Calibri">we grow more Ro</FONT><FONT FACE=3D"Calibri">undup Ready=
 crops and spray them</FONT><FONT FACE=3D"Calibri"> with more Roundup,=
 and our regulators have increased the</FONT> <FONT FACE=3D"Calibri">a=
llowable</FONT></SPAN><SPAN LANG=3D"en-us"> <FONT FACE=3D"Calibri">amo=
unts of Roundup that can be applied</FONT><FONT FACE=3D"Calibri">.&nbs=
p;</FONT></SPAN><SPAN LANG=3D"en-us"> <FONT FACE=3D"Calibri">Those who=
 need to be most concerned are</FONT> <FONT FACE=3D"Calibri">pregnant=
 women</FONT></SPAN><SPAN LANG=3D"en-us"><FONT FACE=3D"Calibri"> o</FO=
NT><FONT FACE=3D"Calibri">r women who may become pregnant who are livi=
ng where Roundup may be sprayed</FONT><FONT FACE=3D"Calibri">, who may=
 be exposed to the drift, etc.</FONT></SPAN><SPAN LANG=3D"en-us">&nbsp=
;<FONT FACE=3D"Calibri"></FONT>&nbsp;<FONT FACE=3D"Calibri"></FONT></S=
PAN><SPAN LANG=3D"en-us"> <FONT FACE=3D"Calibri">(I would also advise=
 any woman who is pregnant or may become pregna</FONT><FONT FACE=3D"Ca=
libri">nt not to use that product at home.)</FONT></SPAN><SPAN LANG=3D=
"en-us"><FONT FACE=3D"Calibri">&nbsp;</FONT></SPAN><SPAN LANG=3D"en-us=
"> <FONT FACE=3D"Calibri">When</FONT> <FONT FACE=3D"Calibri">drugs are=
 reviewed for safety, those that cause malformations in animals are la=
beled as a risk to pregnant women</FONT></SPAN><SPAN LANG=3D"en-us"><F=
ONT FACE=3D"Calibri">, and animal studies are regarded as a pretty goo=
d indicator.&nbsp;</FONT></SPAN><SPAN LANG=3D"en-us"> <FONT FACE=3D"Ca=
libri">Human studies have not been done and would not be ethical</FONT=
></SPAN><SPAN LANG=3D"en-us"> <FONT FACE=3D"Calibri">&#8211;</FONT></S=
PAN><SPAN LANG=3D"en-us"><FONT FACE=3D"Calibri"> but</FONT> <FONT FACE=
=3D"Calibri">there have b</FONT><FONT FACE=3D"Calibri">een reports of=
 a high incidence of birth defects in agricultural communities exposed=
 to</FONT></SPAN><SPAN LANG=3D"en-us"> <FONT FACE=3D"Calibri">pesticid=
e drift in Sou</FONT><FONT FACE=3D"Calibri">th America where Roundup=
 Ready soy is</FONT></SPAN><SPAN LANG=3D"en-us"> <FONT FACE=3D"Calibri=
">grow</FONT><FONT FACE=3D"Calibri">n</FONT></SPAN><SPAN LANG=3D"en-us=
"><FONT FACE=3D"Calibri">, so</FONT></SPAN><SPAN LANG=3D"en-us"> <FONT=
 FACE=3D"Calibri">there is ample cause for concern.&nbsp;</FONT></SPAN=
><SPAN LANG=3D"en-us"> </SPAN></P>

<P DIR=3DLTR><SPAN LANG=3D"en-us"><FONT FACE=3D"Calibri">&nbsp;&nbsp;&=
nbsp;&nbsp;&nbsp; Jim Diamond, M.D.</FONT></SPAN></P>

<P DIR=3DLTR><SPAN LANG=3D"en-us"><FONT FACE=3D"Calibri">&nbsp;&nbsp;&=
nbsp;&nbsp;&nbsp;</FONT></SPAN><SPAN LANG=3D"en-us"><BR>
---<BR>
<FONT FACE=3D"Calibri">*Public kept in the dark on Roundup link with=
 birth defects<BR>
*Industry knew since 1980s, regulators since 1990s<BR>
Earth Open Source<BR>
Press release for immediate release, 7 June 2011<BR>
Contact:</FONT><FONT FACE=3D"Calibri"></FONT></SPAN><SPAN LANG=3D"en-u=
s"> </SPAN><A HREF=3D"mailto:[log in to unmask]"><SPA=
N LANG=3D"en-us"><U><FONT COLOR=3D"#0000FF" FACE=3D"Calibri">claire.ro=
binson</FONT></U></SPAN><SPAN LANG=3D"en-us"><U><FONT COLOR=3D"#0000FF=
" FACE=3D"Calibri">@</FONT></U></SPAN><SPAN LANG=3D"en-us"><U><FONT CO=
LOR=3D"#0000FF" FACE=3D"Calibri">earthopensource.org</FONT></U></SPAN>=
<SPAN LANG=3D"en-us"></SPAN></A><SPAN LANG=3D"en-us"><BR>
<BR>
<FONT FACE=3D"Calibri">Industry and EU regulators knew as long ago as=
 the 1980s-1990s that Roundup, the world's best selling herbicide, cau=
ses birth defects</FONT> <FONT FACE=3D"Calibri">&#8211;</FONT><FONT FA=
CE=3D"Calibri"> but they failed to info</FONT><FONT FACE=3D"Calibri">r=
m the public. This is the conclusion of a new report, &quot;Roundup an=
d birth defects: Is the public being kept in the dark?&quot; co-author=
ed by a group of international scientists and researchers and released=
 today.[1]<BR>
<BR>
The report reveals that industry's own stu</FONT><FONT FACE=3D"Calibri=
">d</FONT><FONT FACE=3D"Calibri">ies (including one commissioned by Mo=
nsanto) showed as long ago as the 1980s that Roundup's active ingredie=
nt glyphosate causes birth defects in laboratory animals.<BR>
<BR>
The German government has known about these findings since at least th=
e 1990s, when as th</FONT><FONT FACE=3D"Calibri">e</FONT><FONT FACE=3D=
"Calibri"> &quot;rapporteur&quot; member state for glyphosate, it revi=
ewed industry's studies for the EU approval of the herbicide. The Euro=
pean Commission has known since at least 2002, when it signed off on=
 glyphosate's approval.<BR>
<BR>
But this information was not made public.</FONT> <FONT FACE=3D"Calibri=
">O</FONT><FONT FACE=3D"Calibri">n the contrary, regulators have consi=
stently misled the public about glyphosate's safety. As recently as la=
st year, the German Federal Office for Consumer Protection and Food Sa=
fety, BVL, told the Commission there was &quot;no evidence of teratoge=
nicity&quot; (abil</FONT><FONT FACE=3D"Calibri">i</FONT><FONT FACE=3D"=
Calibri">ty to cause birth defects) for glyphosate.<BR>
<BR>
BVL made this comment in its rebuttal[2] of an independent scientific=
 study published last year by Argentine scientists. The study showed=
 that Roundup and glyphosate cause birth defects in frogs and chickens=
 at</FONT> <FONT FACE=3D"Calibri">c</FONT><FONT FACE=3D"Calibri">oncen=
trations much lower than those used in agricultural spraying.[3] The=
 study was prompted by reports of high rates of birth defects and canc=
ers in areas of South America growing genetically modified (GM) Roundu=
p Ready soy, which is engineered to tolera</FONT><FONT FACE=3D"Calibri=
">t</FONT><FONT FACE=3D"Calibri">e being sprayed liberally with glypho=
sate herbicide.<BR>
<BR>
In its rebuttal of the Argentine study, BVL cited as proof of glyphosa=
te's safety the industry studies submitted for the Commission's 2002=
 approval of glyphosate (the approval that is currently in forc</FONT>=
<FONT FACE=3D"Calibri">e</FONT><FONT FACE=3D"Calibri">).<BR>
<BR>
But the authors of the new report obtained the approval documents and=
 found that contrary to BVL's claim, industry's own studies, conducted=
 in the 1980s and 1990s, showed that glyphosate/Roundup causes birth=
 defects in experimental animals. In some ca</FONT><FONT FACE=3D"Calib=
ri">s</FONT><FONT FACE=3D"Calibri">es, these effects occurred at low=
 doses.<BR>
<BR>
The German authorities and the EU Commission's ECCO expert review pane=
l[4] whitewashed the findings and the Commission approved the herbicid=
e.<BR>
<BR>
Claire Robinson, a co-author of the new report and spokesperson for t<=
/FONT><FONT FACE=3D"Calibri">h</FONT><FONT FACE=3D"Calibri">e sustaina=
bility NGO Earth Open Source, which published it, said, &quot;This loo=
ks like a thirty-year cover-up by industry and regulators and it has=
 certainly placed the public at risk. Roundup is used not only by farm=
ers but by home gardeners and in school gr</FONT><FONT FACE=3D"Calibri=
">o</FONT><FONT FACE=3D"Calibri">unds and other public areas, in part=
 because of false marketing claims that it is safe.&quot;<BR>
<BR>
Commission delays review of glyphosate<BR>
<BR>
A new, more stringent pesticide regulation comes into force in the EU=
 this June. An objective review of glyphosate under this</FONT><FONT=
 FACE=3D"Calibri"></FONT> <FONT FACE=3D"Calibri">new regulation would=
 almost certainly result in a ban. This is because under the regulatio=
n, independent studies have to be taken into consideration. Many of th=
ese studies, summarised in the new report, show that glyphosate and Ro=
undup cause birth defects,</FONT><FONT FACE=3D"Calibri"> cancer, genet=
ic damage, endocrine disruption, and other serious effects, often at=
 very low doses.<BR>
<BR>
Glyphosate was due to be reviewed in 2012. But late last year, the Com=
mission quietly passed a directive delaying the review of glyphosate=
 and 38 other pes</FONT><FONT FACE=3D"Calibri">t</FONT><FONT FACE=3D"C=
alibri">icides until 2015.[5]<BR>
<BR>
Moreover, in 2015, glyphosate will be reviewed under lax, outdated sta=
ndards. This is because the Commission has failed to complete the data=
 requirements (the tests that industry has to do) for the new regulati=
on in time for industr</FONT><FONT FACE=3D"Calibri">y</FONT><FONT FACE=
=3D"Calibri"> to do the new tests. So glyphosate will likely sail thro=
ugh its 2015 review and will not be reviewed under up-to-date, more st=
ringent data requirements for another 15 years, in 2030.[6]<BR>
<BR>
Claire Robinson said, &quot;Glyphosate could get a free regulatory rid=
e</FONT> <FONT FACE=3D"Calibri">u</FONT><FONT FACE=3D"Calibri">ntil 20=
30, at a time when biotech companies are pressuring the EU for permiss=
ion to cultivate glyphosate-tolerant GM seeds in Europe. This would le=
ad to a huge increase in the use of glyphosate in Europe, as has happe=
ned in North and South America. The be</FONT><FONT FACE=3D"Calibri">n<=
/FONT><FONT FACE=3D"Calibri">eficiary of the Commission's delay will=
 be the pesticide industry; the victim will be public health.<BR>
<BR>
&quot;The Commission must cancel the delay and conduct an immediate re=
view of glyphosate and Roundup, taking into consideration the independ=
ent scientific lit</FONT><FONT FACE=3D"Calibri">e</FONT><FONT FACE=3D"=
Calibri">rature. In the meantime, it must apply the precautionary prin=
ciple and withdraw the herbicide from use in Europe until the review=
 has been completed.&quot;<BR>
<BR>
ENDS<BR>
<BR>
References<BR>
<BR>
1. Antoniou, M., Habib, M., Howard, C.V., Jennings, R.C., Leifert, C.,=
 Nodari, R. O.,</FONT><FONT FACE=3D"Calibri"></FONT> <FONT FACE=3D"Cal=
ibri">Robinson, C., Fagan, J. 2011. Roundup and birth defects: Is the=
 public being kept in the dark? Earth Open Source. June.</FONT></SPAN>=
<SPAN LANG=3D"en-us"> </SPAN><A HREF=3D"http://www.scribd.com/doc/5727=
7946/RoundupandBirthDefectsv5"><SPAN LANG=3D"en-us"><U><FONT COLOR=3D"=
#0000FF" FACE=3D"Calibri">http://www.scribd.com/doc</FONT></U></SPAN><=
SPAN LANG=3D"en-us"><U><FONT COLOR=3D"#0000FF" FACE=3D"Calibri">/</FON=
T></U></SPAN><SPAN LANG=3D"en-us"><U><FONT COLOR=3D"#0000FF" FACE=3D"C=
alibri">57277946</FONT></U></SPAN><SPAN LANG=3D"en-us"><U><FONT COLOR=
=3D"#0000FF" FACE=3D"Calibri">/</FONT></U></SPAN><SPAN LANG=3D"en-us">=
<U><FONT COLOR=3D"#0000FF" FACE=3D"Calibri">RoundupandBir</FONT><FONT=
 COLOR=3D"#0000FF" FACE=3D"Calibri">thDefectsv5</FONT></U></SPAN><SPAN=
 LANG=3D"en-us"></SPAN></A><SPAN LANG=3D"en-us"><BR>
<BR>
<FONT FACE=3D"Calibri">2. BVL, Germany. 2010. Glyphosate</FONT> <FONT=
 FACE=3D"Calibri">&#8211;</FONT><FONT FACE=3D"Calibri"> Comments from=
 Germany on the paper by Paganelli, A. et al. (2010): &quot;Glyphosate=
-based Herbicides Produce Teratogenic Effects on Vertebrates by Impair=
ing Retinoic Acid Signaling&quot;. October 19.</FONT></SPAN><SPAN LANG=
=3D"en-us"> </SPAN><A HREF=3D"http://www.powerbase.info/index.php/File=
:BVL2010.comments.Paganelli.pdf"><SPAN LANG=3D"en-us"><U><FONT COLOR=
=3D"#0000FF" FACE=3D"Calibri">http://www.powerbase.info</FONT></U></SP=
AN><SPAN LANG=3D"en-us"><U><FONT COLOR=3D"#0000FF" FACE=3D"Calibri">/<=
/FONT></U></SPAN><SPAN LANG=3D"en-us"><U><FONT COLOR=3D"#0000FF" FACE=
=3D"Calibri">index.php/File:BVL2010</FONT></U></SPAN><SPAN LANG=3D"en-=
us"><U><FONT COLOR=3D"#0000FF">.</FONT></U></SPAN><SPAN LANG=3D"en-us"=
><U><FONT COLOR=3D"#0000FF" FACE=3D"Calibri">comments.Paganelli.pdf</F=
ONT></U></SPAN><SPAN LANG=3D"en-us"></SPAN></A><SPAN LANG=3D"en-us"><B=
R>
<BR>
<FONT FACE=3D"Calibri">3. Paganelli, A., Gnazzo, V. et al. 2010. Glyph=
osate-based herbicides produce teratogenic effects on</FONT><FONT FACE=
=3D"Calibri"> vertebrates by impairing retinoic acid signaling. Chem=
 Res Toxicol 23(10): 1586</FONT><FONT FACE=3D"Calibri">&#8211;</FONT><=
FONT FACE=3D"Calibri">1595.<BR>
<BR>
4. This review role is now performed by the EFSA's PPR Panel.<BR>
<BR>
5. European Commission. 2010. Commission Directive 2010/77/EU of 10 No=
vember 2010 amending Council Direc</FONT><FONT FACE=3D"Calibri">t</FON=
T><FONT FACE=3D"Calibri">ive 91/414/EEC as regards the expiry dates fo=
r inclusion in Annex I of certain active substances. OJ L 230, 19.8.19=
91.<BR>
<BR>
6. The detailed reasons for this delay are explained in the new report=
. Details as above.</FONT></SPAN><SPAN LANG=3D"en-us"></SPAN></P>

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